Objective To analyze the features of electroencephalography（ EEG） patterns in patients with refractory status epilepticus（RSE）. Methods Sixty patients with Generalized convulsive status epilepticus（ GCSE） were divided into RSE group and non-RSE（ NRSE） group according to the effect of anti-epileptic drugs（ AEDs）. EEG data was compared between two groups. Results In all patients， compared with NRSE group， patients in RSE group showed significantly higher proportion of persistent ictal activity in EEG（ OR=5.44， 95%CI=1.24-23.96，P=0.04）. In 50 patients with intermittent change of EEG， compared with NRSE group， patients in RSE group showed significantly higher proportion of periodic discharges and interictal epileptiform discharges（ OR=29.75，4.12； 95%CI=3.19-277.32， 1.09-15.58；P＜0.05）， and lower proportion of normalization after ictal（ OR=0.11，95%CI=0.01-0.91，P=0.04）. Conclusions Attention should be paid to EEG patterns of persistent ictal activity， occurrence of periodic discharges and interictal epileptiform discharges for the treatment of GCSE.