石家庄城市社区老年人睡眠障碍及认知功能的5 年 随访研究
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国家自然科学基金面上项目(81271489);河北省科学 技术研究与发展计划项目(09276103D);河北省自然科学基金面上项 目(H2014206280)


Sleep disorders and cognitive function in the urban community of Shijiazhuang City in the past five years: a follow-up study
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    摘要:

    目的 探讨河北省石家庄市城市社区60岁以上老年人睡眠障碍与认知功能的关系。 方法 采用整群随机抽样方法,于2010~2011年对石家庄市60岁以上城市社区老年人采用“一对一”访 谈方式进行问卷调查。按照匹兹堡睡眠质量指数(PSQI)总分将老年人分为有睡眠障碍组和无睡眠障碍 组,按照第5个自评条目中第1项与第2项评分,进一步分为入睡困难组,易醒或早醒组以及无睡眠障碍 组。采用简易智力状态检查量表(MMSE)和蒙特利尔认知评估量表(MoCA)评估认知功能水平,对睡眠障 碍与认知功能水平的关系进行分析。结果 共完成103例完整有效问卷,两组受试者性别、年龄、婚姻状 况、居住方式和受教育年限等相匹配,差异无统计学意义(P > 0.05)。5年后随访与基线数据相比睡眠障 碍组的认知功能下降较为明显(P<0.05);入睡困难组较其他组认知功能水平下降明显(P<0.05);易醒或早 醒对认知功能无影响(P>0.05)。结论 老年人的睡眠障碍尤其入睡困难可能是影响认知功能水平的因素。

    Abstract:

    Objective To investigate the relationship between sleep disorders and cognitive function in the urban population aged over 60 in Shijiazhuang, Hebei Province. Methods A questionnaire survey was conducted in the elderly aged over 60 in the urban communities of Shijiazhuang selected by cluster randomized sampling method from 2010 to 2011. According to the total score of Pittsburgh Sleep Quality Index( PSQI), the elderly were divided into sleep disorder group and no sleep disorder group. According to the scores of the first and the second entry in the fifth self-assessment item, they were further divided into difficulty falling asleep group, easy to wake up or wake up early group and no sleep disorders group. The cognitive function was assessed by the Mini-mental State Examination( MMSE) and the Montreal Cognitive Assessment Scale( MoCA), and the relationship between sleep disorders and cognitive function was analyzed. Results There were a total of 103 cases completed and effective questionnaires. There were no significant differences in gender, age, marital status, living style and years of education between the two groups( P> 0.05). After 5 years of follow-up, the cognitive function of the sleep disorder group was significantly lower than that of the baseline data( P< 0.05). The decrease of cognitive function of the difficulty falling asleep group was significant compared with the other groups( P<0.05). It showed no impact on cognitive function in the easy to wake up or wake up early group( P> 0.05). Conclusions Sleep disorder in the elderly, especially difficulty falling asleep, may be the influencing factor of cognitive function.

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孙文洁 王育梅 卢文婷 王学义.石家庄城市社区老年人睡眠障碍及认知功能的5 年 随访研究[J].神经疾病与精神卫生,2017,17(11):
DOI :10.3969/j. issn.1009-6574.2017.11.004.

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  • 在线发布日期: 2018-02-02