化身治疗对精神分裂症患者幻听的临床疗效
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上海交通大学医学院附属精神卫生中心资助课题(2015-YJ-07)


Effects of AVTAR therapy for auditory hallucination of schizophrenia
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    摘要:

    目的 探讨化身治疗对精神分裂症患者幻听的影响。方法 采用随机对照研究方法,将 80 例伴有顽固性幻听的精神分裂症患者随机分为两组,每组40 例。研究组患者在药物治疗的同时合并 化身治疗(干预6 周),对照组予以药物维持治疗和伪化身治疗。采用阳性与阴性症状量表(PANSS)和精 神病性症状评定量表-幻听子量表(PSYRATS-AH)分别于干预前后来评定患者精神症状及幻听的严重 程度。结果 干预后,对照组PANSS 总分、PANSS 幻听分、PSYRATS-AH幻听频率和声音造成的痛苦总 分较基线无明显变化(P> 0.05);研究组PANSS 幻听分、PSYRATS-AH幻听频率和声音造成的痛苦总分 较干预前显著下降(P< 0.05),且低于对照组,但PANSS 总分评分改善不明显(P> 0.05)。结论 化身治 疗能够改善精神分裂症患者的幻听。

    Abstract:

    Objective To investigate the effects of AVTAR therapy for auditory hallucinations in people with schizophrenia. Methods A total of 80 patients with auditory hallucination were randomly assigned to two groups, with 40 cases in each group by random control trail methods. The patients of the study group were given medication therapy combined with AVTAR therapy for 6 weeks, while the patients in the control group were given medication therapy with placebo. Patients' conditions were measured with Positive and Negative Syndrome Scale( PANSS) and Psychotic Rating Scales Auditory Hallucinations( PSYRATS-AH) before and after intervention. Results After intervention, there were no significant changes in the total score of PANSS, auditory hallucination PANSS score, the frequency of PSYRATS-AH and the total score of the pain caused by sound in the study group, comparing with the basic line( P > 0.05). The total score of PANSS, auditory hallucination PANSS score, the frequency of PSYRATS-AH and the total score of the pain caused by sound in the study group decreased significantly than before intervention( P < 0.05) and lower than the control group. However, the change of PANSS total score was not obvious( P > 0.05). Conclusions AVTAR therapy is effective in improving auditory hallucination in schizophrenia patients.

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徐初琛 沈辉 张莉 张毅.化身治疗对精神分裂症患者幻听的临床疗效[J].神经疾病与精神卫生,2018,18(3):
DOI :10.3969/j. issn.1009-6574.2018.03.004.

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  • 在线发布日期: 2018-08-21