Abstract:Depression is a frequent non-motor symptom of Parkinson disease( PD). It may have serious impacts on the quality of life of PD patients and their caregivers. Depressive symptoms in PD often remain unrecognized, as a result, it remains untreated. Although there are many selectable drugs and methods for the treatment of PD depression, there is no evidence of high quality evidence-based medicine. This review illustrates progress of PD depression treatment from respects of drugs, rTMS, deep brain stimulation, electroshock, cognitive behavioral therapy and so on.