Objectives To investigate the sleep quality， mood disorder and thyroid hormone level in patients with chronic subjective dizziness（ CSD）. Methods A cross-sectional self-report survey used to investigate 68 patients with CSD and 60 healthy individuals. The survey included a basic information questionnaire， Self-rating Anxiety Scale（ SAS）， Center for Epidemiologic Studies Depression Scale（ CES-D）， and the Pittsburgh Sleep Quality Index（ PSQI）. The differences in thyroid hormone levels between the two groups were compared by blood sampling assay. Results The total scores of PSQI， sleep time， sleep efficiency， sleep disorder， and sleep pill usage rate in the CSD group were significantly higher than those in the control group （P＜0.01）. The total score of SAS was（ 52.48±14.17）， and the total score of CES-D was（ 17.51±9.47）. 63.2% （43/68） of the patients have anxiety， and 66.2%（ 45/68） have depression. Comparison between the two groups' thyroid hormone levels suggested that although the mean values of the two groups were within the normal range， thyroid stimulating hormone（ TSH） levels increased in the CSD group and free triiodothyronine T3（ fT3） and free thyroxine T4（ fT4） levels decreased compared with the control group. There was a statistical difference in the proportion of patients with low fT4 between the two groups（ P＜ 0.05）. Conclusions CSD patients generally have emotional and sleep problems. Neuroendocrine factors， especially thyroid level， may be one of the influencing factors， which needs to be further studied.