Uric acid（ UA） is produced by human exogenous intake and purine compounds in liver metabolism， which is known to have an impact on hypertension， diabetes， chronic kidney disease and gout. Studies have shown that it is a risk factor for cardiovascular disease. However， its impact on cognitive function is still controversial. With the aging of the social population， the number of people with cognitive dysfunction increases， which is a great burden for society and the family. At present， there is no good treatment for cognitive dysfunction， and it is extremely important to actively control risk factors and prevent the occurrence of cognitive dysfunction.