Objectives To systematically evaluate the efficacy of Naikan cognitive therapy in PANSS patients with schizophrenia in China. Methods Databases including PubMed、Embase、Cochrane、Medline、 Web of science、 CBM、CNKI、VIP、WanFang Data、TWS. We searched databases to collect PANSS related randomized controlled trials of patients with schizophrenia treated used Naikan cognitive therapy. RevMan 5.3 software was used for meta-analysis. Results A total of 9 randomized controlled trials were included， 389 cases of experimental group and 393 cases of control group.The results showed that the total PANSS score，positive symptoms score，negative symptoms score and general psychopathological symptoms score of schizophrenia patients could be reduced by Naikan cognitive therapy（ P＜0.05）. Conclusions To some extent， Naikan cognitive therapy is helpful to improve the clinical symptoms of schizophrenia， especially general psychopathological symptoms and negative symptoms.