Objectives To investigate the prevalence of dyslipidemia in adults after stress in fetuses and infants, and to analyze the influencing factors. Methods This study is a cross-sectional study, recruited a total of 1 260 cases of the demographic characteristics from Kailuan Mining Group. According to the date of birth, there were 372 cases of infancy exposure group, 382 cases of fetal exposure group and 506 cases of unexposed group. The biochemical indexes of blood( FBG), triglyceride( TG), cholesterol( TC), high density lipoprotein cholesterol( HDL-C) and low density lipoprotein cholesterol( LDL-C) were evaluated. Results The rate of the prevalence of high TC hyperlipidemia and mixed hyperlipidemia in infant exposure group was higher than that of fetal exposure group( 18.8% vs 11.3%,13.4% vs 6.8%,P<0.05); the prevalence of dyslipidemia in infants exposure group was higher than that of unexposed group( 40.0% vs 27.7%,P<0.05). Single factor analysis of drinking, body mass index, and earthquake stress group were related factors of dyslipidemia (χ2=4.432,6.612,7.690;P < 0.05). The unconditional Logistic regression analysis showed that the risk of dyslipidemia was 1.590 times as high as that of non drinkers( OR=1.590, 95%CI=1.102-2.294). The risk of dyslipidemia in infant exposure group was 1.723 times higher than that in the unexposed group( OR=1.723, 95%CI=1.147-2.589). The BMI wasting type was more protective than the overweight / obese type( OR=0.280, 95%CI=0.080-0.972). Conclusions The prevalence of high TC, mixed hyperlipidemia and dyslipidemia is higher in infants exposure group. Low body weight is a protective factor for dyslipidemia. Alcohol consumption and infant exposure are risk factors of dyslipidemia.