Depression is characterized by long course of disease， high recurrence rate， high disability rate and high suicide rate. As a family member of patients with depression， it is easy to produce a caregiver burden， which in turn negatively affects the mental health of the caregiver， the continuous treatment and prognosis of the patient. The main factors affecting the caregiver's burden can be put into three aspects： caregiver's own factors， patient's clinical factors and economic level. Mental health education， cognitive behavioral therapy and network-based psychological intervention are the current commonly used approaches to reduce the caregiver's burden in China.