Abstract:Transcranial direct current stimulation( tDCS) is a non-invasive brain stimulations technique, with characteristics of low-cost and portability. Many scholars believe that it may be a potential new way to treat depressive disorder. At present, the research on the treatment of depression in general population mainly focuses on optimizing the treatment protocols, and the results of different treatment protocols are inconsistent. Although the research on the treatment of depressive disorder in particular population is still in its infancy, some preliminary results have been achieved. This article reviews the research progress of tDCS on depression in different populations in recent years, with a view to providing some evidence-based evidence.