Objective To explore the risk factors for bleeding during spinal hemangioblastoma surgery. Methods A retrospective study was conducted among 69 spinal hemangioblastoma patients who underwent selective surgeries at Beijing Tiantan Hospital， Capital Medical University from January 2016 to December 2018. The risk factors for blood loss of spinal hemangioblastoma surgery were analyzed. Results There were 37 male （53.6%） and 32 female （46.4%） patients. The amount of bleeding was 50-1 200 ml， with an average （273±124） ml. The operation was divided into low-risk group （bleeding volume ＜ 300 ml） 58 cases and highrisk group （bleeding volume ≥ 300 ml） 11 cases. Multivariate analysis showed that tumor location （OR=1.400）， recurrence （OR=1.350）， severe adhesion （OR=2.211） and resection degree （OR=2.052） were related to the increase of bleeding volume in spinal angioreticuloma surgery. Conclusions For the hemangioblastoma of the spinal cord， which is located in the ventral side of the spinal cord， recurrences， severe adhesion of the tumor， and subtotal resection of the tumor， we should be alert to the possibility of increased bleeding during the operation， and make preparations to prevent massive bleeding.