Abstract:Panic disorder( PD) and generalized anxiety disorder( GAD) are two main types of anxiety disorders. The pathogenesis of these two diseases is complex and often comorbid. Studies have shown that abnormal activation or metabolism in specific location of the brain plays an important role in the pathogenesis of these two diseases. At present, drug therapy and psychological intervention are the main treatment methods for both of them. Although these therapies have certain effects, their efficacy is not obvious enough. In recent years, repetitive transcranial magnetic stimulation( rTMS), as a new neuromodulation technique, has been recommended for the treatment of anxiety disorders due to its significant efficacy and safety. The therapeutic mechanisms of rTMS for these two diseases are complex and different. This article aims to summarize and analyze the relevant mechanisms of rTMS in the treatment of PD and GAD, and clarify the similarities and differences between them, in order to provide relevant clues for the precision treatment of PD and GAD in the future.