重复经颅磁刺激对惊恐障碍及广泛性焦虑障碍治疗 机制的研究进展
作者:
作者单位:

作者简介:

通讯作者:

基金项目:

国家自然科学基金青年科学基金项目(81801345);广东省科技计划项目(2019B0303 16001)


Research progress of the therapeutic mechanisms of repetitive transcranial magnetic stimulation on panic disorder and generalized anxiety disorder
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    惊恐障碍和广泛性焦虑障碍(GAD)是焦虑障碍的两种主要类型,两种疾病的发病机制复 杂且常共病。研究表明脑部特定区位异常活化或代谢作用对两者发病有重要影响。目前对于两者的 治疗手段主要为药物治疗和心理干预,以上疗法虽有一定疗效但不够明显。近年来,重复经颅磁刺激 (rTMS)作为新型的神经调控技术,其有效性、安全性等特性显著,被推荐用于焦虑障碍治疗中。rTMS 对 于上述两种疾病的治疗机制复杂且存在差异。现总结并分析关于rTMS 治疗惊恐障碍和GAD 的相关机 制,明确两者之间的异同,为精准地治疗惊恐障碍和GAD 提供相关线索。

    Abstract:

    Panic disorder( PD) and generalized anxiety disorder( GAD) are two main types of anxiety disorders. The pathogenesis of these two diseases is complex and often comorbid. Studies have shown that abnormal activation or metabolism in specific location of the brain plays an important role in the pathogenesis of these two diseases. At present, drug therapy and psychological intervention are the main treatment methods for both of them. Although these therapies have certain effects, their efficacy is not obvious enough. In recent years, repetitive transcranial magnetic stimulation( rTMS), as a new neuromodulation technique, has been recommended for the treatment of anxiety disorders due to its significant efficacy and safety. The therapeutic mechanisms of rTMS for these two diseases are complex and different. This article aims to summarize and analyze the relevant mechanisms of rTMS in the treatment of PD and GAD, and clarify the similarities and differences between them, in order to provide relevant clues for the precision treatment of PD and GAD in the future.

    参考文献
    相似文献
    引证文献
引用本文

李南曦 罗昕 李春波 张宾.重复经颅磁刺激对惊恐障碍及广泛性焦虑障碍治疗 机制的研究进展[J].神经疾病与精神卫生,2020,20(10):
DOI :10.3969/j. issn.1009-6574.2020.10.010.

复制
文章指标
  • 点击次数:
  • 下载次数:
历史
  • 收稿日期:
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2021-01-06