Abstract:Parkinson disease patients often have cognitive impairment in the middle and late stage of the disease, which seriously affects their social function and quality of life. According to the differences in motor symptoms, Parkinson disease patients can be divided into motor types. There are differences in the incidence of cognitive impairment and cognitive impairment in different motor subtypes, among which the neurotransmitter network disorder plays a key role. This paper reviews the research of neurotransmitter network on motor subtypes and cognitive function in Parkinson disease in recent years, and reviews the classification of motor subtypes in Parkinson disease, the correlation between different motor subtypes and cognitive impairment, and neurotransmitter theory.