Objective To explore the relationship between suicidal attempt（ SA） and clinical characteristics in adolescent patients with mood disorders with non-suicidal self injury（ NSSI） behavior. Methods A total of 80 adolescent mood disorder patients aged 13-19 years were enrolled from inpatient unit of Beijing Anding Hospital from December 2020 to August 2021. Those patients with a history of NSSI were included in this analysis for a cross-sectional investigation. The self-designed general information questionnaire， adolescent NSSI behavior questionnaire， Simple Coping Style Questionnaire（ SCSQ）， Chinese version of Positive and Negative Affect Schedule（ PANAS） and Childhood Trauma Questionnaire（ CTQ） were used in the evaluation. According to presence or absence of a history of SA in the last year， the patients were divided into two groups： the NSSI group（ n=33） and the NSSI+SA group（ n=47）. The variables with statistical significance in univariate analysis were incorporated into the multivariate Logistic regression model for analysis. Results Univariate analysis showed that the proportion of patients under 16 years old（ including 16 years old）， female， relapse patients， first episode age under 14 years old， NSSI frequency over 40 times（ including 40 times） in NSSI+SA group was higher than that in NSSI group， and the score of emotional abuse was higher than that in NSSI group， the differences were statistically significant（ P＜0.05）. The proportion of patients who hit hard objects with fists in NSSI group was higher than that in NSSI + SA group, and the proportion of patients who cut with blades was lower than that in NSSI+SA group（ P ＜ 0.05）. Multivariate Logistic regression model showed that younger age（ ≤16 years old）， the method of knife cutting， high frequency of NSSI（ ≥40 times）， and recurrence were significant influencing factors for the co-occurrence of NSSI+SA. Conclusions The incidence of SA in adolescent mood disorder patients with NSSI is high， and SA more likely to occur in patients with lower age， self-injury by cutting， high frequency of self-injury and recurrence.