Objective To explore and analyze the related factors of suicidal behavior in hospitalized patients with early adult bipolar disorder. Methods A total of 521 inpatients with bipolar disorder in early adulthood (aged between 18 to 25) in Beijing Anding Hospital affiliated to Capital Medical University from January to December 2018 were recruited as the research subjects. They were divided into suicide group (n=140) and no suicide group (n=381) according to whether they had ever committed suicide. The general data and disease subtypes of the two groups were compared. The risk factors related to suicide in early adult patients with bipolar disorder were analyzed by binary Logistic regression analysis. Results Compared with the suicide group, there were more female in the suicide group [70% (98/140) vs 47.8% (182/381), χ2 =20.350, P< 0.01], more impulsive personality [29.3% (41/140) vs 19.2% (73/381), χ2 =6.141, P=0.013], and there were more people with a history of major trauma [14.3% (20/140) vs 4.5% (17/381), χ2 =16.941, P< 0.01]. The differences were statistically significant. Binary Logistic regression analysis showed female [OR=0.375, 95%CI (0.226-0.564)], impulsive personality [OR=0.603, 95%CI (0.377-0.963)], history of major trauma [OR=0.295, 95%CI (0.144-0.604)]were the independent risk factors for suicidal behavior in patients with bipolar disorder in early adulthood (P< 0.05). Conclusions Patients with bipolar disorder in early adulthood who are females, have longer disease course, have impulsive personality, and have a history of major trauma are at higher risk of suicide.
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孙丛丛,吴涵,贾立娜,潘伟刚.住院成年早期双相情感障碍患者自杀相关因素研究[J].神经疾病与精神卫生,2022,22(6): DOI :10.3969/j. issn.1009-6574.2022.06.009.