Objective To investigate difference between Mood Disorder Questionnaire (MDQ) and 32 Items Hypomania Check List (HCL-32) in screening manic/hypomanic symptoms in patients with depressive disorders in psychiatric hospitals and detection rate, as well as the difference in clinical characteristics between negative and positive patients. Methods A total of 105 patients with depressive disorders in the inpatient department and outpatient of Beijing Anding Hospital Affiliated to Capital Medical University from September 2014 to December 2015 were selected as the research subjects. MDQ and HCL-32 were applied to investigate previous hypomanic/manic symptoms. The total score of MDQ ≥ 7 and the total score of HCL- 32 ≥ 14 were positive for previous hypomanic/manic symptoms. The positive detection rate of the two scales and the clinical characteristics of positive and negative patients were compared. The reliability of the scale was tested by Cronbach's α. Results The Cronbach's α of the MDQ was 0.784 (95%CI=0.718-0.840, P < 0.01); the Cronbach's α of the HCL-32 was 0.943 (95%CI=0.926-0.958, P < 0.01). The positive rate of MDQ screening was 15.24% (16/105), which is lower than that of HCL-32 screening positive rate 40.95% (43/105), and the difference was statistically significant (P < 0.01). The consistency of the two scales is low,and the difference is statistically significant (Kappa=0.281, P< 0.01). Among the positive patients screened by MDQ, 7/16 was accompanied by suicidal ideas, attempts or behaviors, and 6/16 was accompanied by atypical depressive symptoms, which was higher than 29.21% (26/89) and 13.48% (12/89) of the negative patients, and the difference was statistically significant (P< 0.05). Conclusions The detection rate of previous hypomania/ mania symptoms in patients with depression by HCL-32 is higher than that of MDQ, and depression patients with positive screening have a high risk of suicide, accompanied by atypical depression characteristics.
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付兆燕,毛珍,孙悦,李峰,李田,王传跃,薄奇静.心境障碍问卷和32项轻躁狂症状清单在抑郁症患者中的应用[J].神经疾病与精神卫生,2022,22(8): DOI :10.3969/j. issn.1009-6574.2022.08.004.