Schizophrenia is a severe mental disorder in which the structure and function of the brain are abnormal. Early detection and intervention in the prodromal stage of schizophrenia can greatly improve their prognosis. At present, there is still a few of objective indicators for the early identification of clinical high risk of psychosis (CHR). With the development of neuroimaging technology, many studies are committed to finding biomarkers of CHR gray matter through brain structural magnetic resonance imaging. Related studies have reported the abnormalities of cortical and subcortical imaging in CHR, but there are few consistent conclusions. This paper reviews the research progress of CHR structural magnetic resonance imaging, to provide reference for clinical practice and future research.
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王怡梦,薄奇静,李田,赵蕾,王传跃.精神病临床高危灰质结构的研究进展[J].神经疾病与精神卫生,2022,22(8): DOI :10.3969/j. issn.1009-6574.2022.08.007.