小脑靶向神经刺激促进吞咽恢复机制的研究进展
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黑龙江省自然科学基金联合引导项目(LH2019H051)


Mechanisms of swallowing recovery facilitated by cerebellar targeted neurostimulation
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    摘要:

    大脑的经颅磁刺激和电刺激是目前具有一定应用前景的技术,逐渐在基础研究和临床实 践中得到应用。这种无创的、非侵入性的靶向神经刺激,通过调节神经兴奋性和可塑性来改善或恢复 大脑功能。由于小脑在运动协调、联想和情感等方面与大脑存在神经解剖和功能联系,因此以小脑为 靶点的神经刺激可以更好地了解生理及病理状态下,小脑与大脑吞咽运动区之间的联系,更好地研究 小脑对吞咽皮质区域兴奋性的调节作用,以及对吞咽功能的影响,为神经源性吞咽障碍提供一种潜在 的治疗方法。

    Abstract:

    Transcranial magnetic stimulation and electrical stimulation of the brain are very promising technologies, and are gradually being applied in basic research and clinical practice. This non-invasive, noninvasive targeted neural stimulation improves or restores brain function by modulating neural excitability and plasticity. Because the cerebellum has neuroanatomical and functional connections with the brain in motor coordination, association and emotion, nerve stimulation targeting the cerebellum can help with better understanding of the relationship between the cerebellum and the swallowing motor area of the brain under physiological and pathological conditions, and better study the regulation of cerebellum on the excitability of swallowing cortex and its effect on swallowing function, so as to provide a potential treatment for neurogenic swallowing disorder.

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白林,梅继林,李庆琳,李晓宁.小脑靶向神经刺激促进吞咽恢复机制的研究进展[J].神经疾病与精神卫生,2022,22(9):
DOI :10.3969/j. issn.1009-6574.2022.09.012.

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  • 在线发布日期: 2022-09-21