青少年抑郁症患者的社会决策行为研究
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首都医科大学附属北京安定医院院级课题(YX2019-05,YX2021-06)


Research on social decision-making behaviors of adolescent depression patients
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    摘要:

    目的 探讨青少年抑郁症患者社会决策行为的异常,比较其社会功能情况。方法 选取 2020 年 9 月至 2021 年 2 月在北京安定医院门诊就诊或住院的 49 例青少年抑郁症患者,以及在附近社区 招募的 25 名健康对照者为研究对象。采用 17 项汉密尔顿抑郁量表(HAMD-17)、患者健康问卷抑郁量表 (PHQ-9)、广泛性焦虑量表(GAD-7)比较两组受试者的抑郁、焦虑情况。采用重复测量方差分析比较两 组受试者对于最后通牒博弈范式方案的接受率和反应时的差异,并于任务结束后采用任务后问卷评估 两组受试者对方案公平性的认知差异。结果 抑郁症组患者的 HAMD-17、PHQ-9 和 GAD-7评分高于健 康对照组,差异有统计学意义(P< 0.05)。两组受试者的接受率比较,差异无统计学意义(P> 0.05)。在 接受率方面,公平性的主效应有统计学意义(F=201.760,P< 0.01,partial η2 =0.737),公平性与提议者类 别之间存在交互作用(F=8.791,P< 0.01,partial η2 =0.109)。两组受试者的反应时比较,差异无统计学意 义(P> 0.05)。在反应时方面,方案公平性的主效应有统计学意义(F=42.755,P< 0.01,partial η2 =0.373), 方案提议者的主效应有统计学意义(F=5.333,P< 0.05,partial η2 =0.069),公平性与提议者之间存在交互 作用(F=8.946,P< 0.01,partial η2 =0.111)。两组受试者的任务后问卷总分比较,差异无统计学意义(P> 0.05),但抑郁症组任务后问卷中问题 1 的评分为 6.4(1.0,10.0)分,低于健康对照组的 8.0(2.0,10.0)分, 差异有统计学意义(Z=-3.235,P< 0.01)。结论 青少年抑郁症患者的社会决策行为未见明显异常,这 与其对分配方案的公平性认知相关。

    Abstract:

    Objective To explore the abnormal social decision-making behavior of adolescent depression patients, so as to reflect the problem of its social function. Methods From September 2020 to February 2021, a total of 49 adolescent patients who were treated in outpatient or inpatient department of Beijing Anding Hospital and 25 healthy adolescents in community were selected as research subjects. Hamilton Depression Scale-17 (HAMD-17), the Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder (GAD-7) were applied to assess patients' depression and anxiety symptoms. The repeated measurement ANOVA was used to compare the difference in the acceptance rate and reaction time of the ultimatum game paradigm scheme between the two groups of subjects, and the post task questionnaire was used to assess the cognitive difference between the two groups of subjects on the fairness of the scheme after the task was completed. Results The HAMD-17, PHQ-9, and GAD-7 scores of patients in the depression group were higher than those in the healthy control group, with statistically significant differences (P< 0.05). There was no statistically significant difference in acceptance rates between the two groups of subjects (P> 0.05). In terms of acceptance rate, the main effect of fairness is statistically significant (F=201.760, P< 0.01, partial η2 =0.737), and there is an interaction between fairness and proposer categories (F=8.791, P < 0.01, partial η2 =0.109). There was no statistically significant difference in reaction time between the two groups of subjects (P > 0.05). In terms of reaction time, the main effect of scheme fairness is statistically significant (F=42.755, P < 0.01, partial η2 =0.373), and the main effect of the scheme proposer is statistically significant (F=5.333, P < 0.05, partial η2 =0.069). There is an interaction between fairness and proposers (F=8.946, P< 0.01, partial η2 =0.111). There is no statistically significant difference in the total score of the post task questionnaire between the two groups of subjects (P> 0.05). However, the score of question 1 in the post-task questionnaire of the depression group was 6.4 (1.0, 10.0) points, which was lower than the 8.0 (2.0, 10.0) points of the healthy control group, with a statistically significant difference (Z=-3.235, P< 0.01). Conclusions There is no significant abnormality in the social decision-making behavior of adolescent depression patients, which is related to their understanding of fairness in allocation plans.

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尹胜健,袁晓菲,陈旭,郑毅.青少年抑郁症患者的社会决策行为研究[J].神经疾病与精神卫生,2023,23(6):
DOI :10.3969/j. issn.1009-6574.2023.06.007.

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  • 在线发布日期: 2023-07-14