Objective To explore the impact of clinical symptoms and executive function on self-esteem in children with attention deficit hyperactivity disorder （ADHD）. Methods From June 2017 to September 2018， a total of 122 children aged 8 to 12 years with ADHD who visited the pediatric clinic of Shanghai Mental Health Center were selected as the study group. At the same time， 66 healthy children from grade 2 to grade 6 in a primary school in Jiading District of Shanghai were selected as the control group. Compare the selfesteem of the two groups using the Piers-Harris Children's Self-Concept Scale （PHCSS）. The clinical symptoms and executive function of children in the study group were investigated using the Swanson Nolan and PelhamVersion Ⅳ （SNAP- Ⅳ）， Stroop Color-Word Test （SCWT）， and the Wechsler Intelligence Scale for Children Version Ⅳ （WISC-Ⅳ）. Pearson correlation analysis was used to analyze the correlation between PHCSS scores， clinical symptoms， and executive performance in children with ADHD. Multiple linear regression was used to analyze the influencing factors of self-esteem in children with ADHD. Results The total score and scores of various dimensions of PHCSS in the study group were lower than those in the control group， and the differences were statistically significant （t=-6.18-2.24， P ＜ 0.01）. The Pearson correlation analysis results showed that the correct reading of Table B in SCWT was positively correlated with the total score， social dimension score，and happiness and satisfaction dimension score of PHCSS （r=0.24， 0.26，0.19；P＜ 0.05）， while hyperactivity impulse in SNAP-Ⅳ was positively correlated with the scores of intelligence and school situation dimensions， body and appearance attribute dimensions in PHCSS （r=0.19，0.23；P ＜ 0.05）. The hyperactivity impulses in SNAP- Ⅳ and the correct reading of Table B in SCWT are influencing factors for self-esteem in children with ADHD （t=2.818，3.041；P＜ 0.05）. Conclusions The level of self-esteem of ADHD children is lower than that of healthy children. The self-esteem level of ADHD children is affected by hyperactivity symptoms and the ability of individual response inhibition.