Objective To explore the influence of violence experience within 6 months prior to onset of bipolar disorder on life satisfaction and social function. Methods A total of 240 bipolar disorder patients who underwent 12 weeks of effective treatment in the acute phase from June 2014 to June 2017 at Beijing Anding Hospital affiliated with Capital Medical University were selected as the research subjects. A selfdesigned general data questionnaire was applied to collect demographic and clinical data. The Sexual and Physical Violence Questionnaire was applied to collect the violence experience within 6 months prior to the onset this time. Residual symptoms were assessed by 17-items Hamilton Depression Rating Scale (HAMD-17) and Young Mania Rating Scale (YMRS) and life satisfaction and social function were assessed by WHO Quality of Life-BREF (WHOQOL-BREF) and Sheehan Disability Scale (SDS) at baseline, 3 months and 6 months. Results Within 6 months prior to the onset, 38.8% (93/240) of patients experienced violence, of which 28.0% (26/93) had experienced sexual violence, 72.0% (67/93) had experienced physical violence, and 80.6% (75/93) had experienced sexual and physical violence. There is a statistically significant difference in marital status, suicidal attitudes, suicide plans, and total number of episodes in the past three years between patients with and without violent experiences (P< 0.05). A total of 194 patients were included in the analysis at a 3-month followup, and 171 patients were included in the analysis at a 6-month follow-up. There was a statistically significant difference in the total HAMD-17 score between patients with and without violent experiences at baseline and 3-month follow-up (Z=-2.24,-1.99;P < 0.05), while there was no statistically significant difference in the total HAMD-17 score at 6-month follow-up (Z=-1.28,P > 0.05). There was no statistically significant difference in the total YMRS scores between the two groups of patients at three time points (Z=-0.81,-1.13, -1.00;P> 0.05). Patients with violent experiences had lower scores in the psychological, social relations, and environmental fields in WHOQOL-BREF at baseline and 3-month follow-up compared to patients without violent experiences, with a statistically significant difference (Z=-3.65-2.16;P < 0.05). Among them, the scores in the social relations field were still lower than those in patients without violent experiences at 6-month followup, with a statistically significant difference (Z=-2.28, P< 0.05). The proportion of cases of work/study, social life, and family life damage in patients with violent experiences at 3-month follow-up is higher than that in patients without violent experiences, and the difference is statistically significant (χ2 =4.22-6.63; P < 0.05). There was no statistically significant difference in the work/study, social life, and family life damage between the two groups at baseline and 6-month follow-up (χ2 =0.06-1.78; P > 0.05). Conclusions The experience of violence within 6 months prior to this episode had a significant impact on the life satisfaction and social function of bipolar disorder patients in the acute phase within 3 months after treatment, and the impact gradually disappeared after 6 months.
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黄娟,吕楠,赵茜,付冰冰,张玲.暴力经历对双相障碍患者生活满意度及社会功能的 影响[J].神经疾病与精神卫生,2023,23(9): DOI :10.3969/j. issn.1009-6574.2023.09.002.