Many diseases are accompanied by cognitive impairment during their occurrence and development, and cognitive impairment has adverse effects on the course and prognosis of the disease. The N-methyl-D-aspartate receptor 2B subunit (GRIN2B) gene is associated with synaptic plasticity and therefore has a potential association with cognitive impairment. This article reviews the research on the correlation between GRIN2B gene expression, gene polymorphism, and epigenetics with cognitive impairment, in order to explore the potential mechanisms of cognitive impairment.
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余浩,邹韶红. N-甲基-D-天冬氨酸受体2B亚基基因遗传 与认知功能损害关系的研究进展[J].神经疾病与精神卫生,2023,23(9): DOI :10.3969/j. issn.1009-6574.2023.09.013.