Type 1 narcolepsy is characterized by the decrease of hypocretin-1 level in cerebrospinal fluid. The main clinical manifestations of NT1 type are uncontrollable excessive daytime sleepiness, cataplexy, sleep paralysis, sleep disorder at night, and often accompanied by psychotic symptoms such as hallucinations before falling asleep. The psychotic symptoms of NT1 patients are complex and diverse, and psychotic symptoms are also the core symptoms of schizophrenia, which may bring difficulties to the diagnosis and treatment of both. Therefore, this article reviews the correlation between psychotic symptoms and schizophrenia in patients with NT1 and the treatment plan, in order to improve the clinicians' ability to identify them,improve their understanding of the possibility of comorbidity,reduce the misdiagnosis rate, and provide more effective treatment for patients.
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郭静仪,李艳红,帅军君.1型发作性睡病与精神分裂症相关性及治疗的研究进展[J].神经疾病与精神卫生,2024,24(1): DOI :10.3969/j. issn.1009-6574.2024.01.010.