磁共振成像在青少年抑郁非自杀性自伤行为研究中的应用进展
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内蒙古医学科学院公立医院科研联合基金科技项目 (2023GLLH0147)


Progress of MRI for non-suicidal self-injury in adolescents with depression
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    摘要:

    青少年抑郁症主要是由于社会、遗传等因素所致,表现为青少年自我否定、痛苦等负面情 绪的一种临床综合征,而非自杀性自伤(NSSI)行为则是其较为常见的一种伴随症状。NSSI 是指个体在 没有明确自杀意图的情况下故意、反复地伤害自己身体的一类行为。这种自伤行为并非出于自杀意图, 而是一种应对内心痛苦和负面情绪的方式。NSSI 行为在青少年中较为普遍,对其身心健康产生严重影 响。临床研究显示,出现 NSSI 行为的青少年抑郁症患者往往存在神经系统影像学差异,其发生可能与 脑结构和功能改变有关。基于此,本文对近年来将磁共振成像(MRI)技术用于 NSSI 行为研究的相关进 展进行分析、总结,以期为 NSSI 行为的发病机制及临床研究提供参考。

    Abstract:

    Adolescent depression is mainly caused by social, genetic and other factors, manifested as a clinical syndrome of negative emotions such as self-denial and pain in adolescents, while non-suicidal self-injury (NSSI) behavior is a common accompanying symptom. NSSI refers to a type of behavior in which an individual intentionally and repeatedly harms their body without a clear suicidal intention. This kind of selfinjury behavior is not out of suicidal intention, but a way to deal with inner pain and negative emotions. NSSI behavior is common in adolescents, which has a serious impact on their physical and mental health. Clinical studies have shown that adolescents depression patients with NSSI behavior often exhibit neurological imaging differences, which may be related to changes in brain structure and function. Based on this, this paper analyzes and summarizes the research progress of behavioral magnetic resonance imaging (MRI) technology of NSSI in recent years, to provide reference for the pathogenesis research of NSSI behavior and clinical research.

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景兰,张蔷,王学斐,陶格斯,张川江.磁共振成像在青少年抑郁非自杀性自伤行为研究中的应用进展[J].神经疾病与精神卫生,2024,24(7):483-488
DOI :10.3969/j. issn.1009-6574.2024.07.005.

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  • 在线发布日期: 2024-08-12