Objective To explore the effects of deep transcranial magnetic stimulation （dTMS） combined with drug therapy on anxiety， depression， and social function in patients with depressive disorder. Methods From September 2022 to December 2023， 149 patients with depressive disorder at the Mental Health Center of the First Hospital of Hebei Medical University were selected as participants. The patients were randomly divided into dTMS combined with drug therapy group （n=70） and drug therapy group （n=79） using a random number table method. Drug therapy group was treated with a single antidepressant， while dTMS combined drug therapy group was treated with dTMS in addition to the drug therapy， five times a week for a total of two weeks. Before treatment and two weeks after treatment， the 17 item Hamilton Depression Scale （HAMD-17）and Hamilton Anxiety Scale （HAMA） were used to evaluate the depression and anxiety symptoms of the two groups of subjects， and the Global Assessment Functioning Scale （GAF） was used to evaluate the social function of the subjects. Statistical methods such as independent sample t-test and chi square test were used to compare the efficacy differences between the two groups. Results The differences in HAMA ［（26.10±8.60） vs （12.87±4.54）， （26.89±6.98） vs （12.34±4.91）］， HAMD-17 ［（26.43±6.40） vs （11.46±4.58）， （26.83±4.62） vs （9.30±5.33）］， and GAF ［（41.00±9.30） vs （52.36±11.31）， （42.23±11.49） vs （58.54±15.31） ］ scores before and after treatment between drug therapy group and dTMS combined with drug therapy group were statistically significant （t=13.95， 17.29， 19.15， 21.77， -11.95， -12.26； all P＜ 0.05）. After two weeks of treatment， there was no statistically significant difference in the HAMA score reduction rate ［（0.46±0.27）vs （0.53±0.19）］ between drug therapy group and dTMS combined with drug therapy group （t=-1.73， P=0.09）. There was a statistically significant difference in the HAMD-17 score reduction rate ［（0.55±0.19） vs （0.64±0.20）］ between the two groups （t=-2.90， P＜ 0.05）. The scoring rate of the GAF scale in the dTMS combined with drug therapy group was higher than that in the drug group ［（0.46±0.25）vs （0.30±0.23）］，and the difference was statistically significant（t=-2.81，P＜ 0.05 ）. Conclusions DTMS combined with drug therapy can rapidly improve anxiety and depression in patients with depressive disorder， and promote the improvement of social function