Objective To compare the clinical characteristics of hospitalized patients with late life depression (LLD) at different suicide risks in the acute phase, and explore the related factors of suicide risks. Methods A retrospective analysis was conducted on 118 patients with LLD at risk of suicide, admitted to Beijing Anding Hospital, Capital Medical University during acute phase from July 2021 to December 2022, including 65 with suicidal ideation(suicidal ideation group) and 53 with attempted suicide behaviour(attempted suicide group). The general clinical data, and the scores of Hamilton Anxiety Rating Scale (HAMA) and Hamilton Depression Rating Scale-24 (HAMD-24) were compared. The following pathology results among patients in different groups were compared, including adrenocorticotropic hormone(ACTH), cortisol, serum total thyroxine(TT4), triiodothyronine(T3), free triiodothyronine(FT3), free thyroxine(FT4), thyroid-stimulating hormone(TSH), total cholesterol(TC), triglycerides(TG), high-density lipoprotein cholesterol(HDL-C), low-density lipoprotein cholesterol(LDL-C), estradiol, testosterone, etc. The related factors of attempted suicide in hospitalized LLD patients were analyzed by binomial logistic regression. Results Compared with the suicide ideation group, the FT3 level was lower in the attempted suicide group. Compared with the suicide ideation Objective To compare the clinical characteristics of hospitalized patients with late life depression (LLD) at different suicide risks in the acute phase, and explore the related factors of suicide risks. Methods A retrospective analysis was conducted on 118 patients with LLD at risk of suicide, admitted to Beijing Anding Hospital, Capital Medical University during acute phase from July 2021 to December 2022, including 65 with suicidal ideation(suicidal ideation group) and 53 with attempted suicide behaviour(attempted suicide group). The general clinical data, and the scores of Hamilton Anxiety Rating Scale (HAMA) and Hamilton Depression Rating Scale-24 (HAMD-24) were compared. The following pathology results among patients in different groups were compared, including adrenocorticotropic hormone(ACTH), cortisol, serum total thyroxine(TT4), triiodothyronine(T3), free triiodothyronine(FT3), free thyroxine(FT4), thyroid-stimulating hormone(TSH), total cholesterol(TC), triglycerides(TG), high-density lipoprotein cholesterol(HDL-C), low-density lipoprotein cholesterol(LDL-C), estradiol, testosterone, etc. The related factors of attempted suicide in hospitalized LLD patients were analyzed by binomial logistic regression. Results Compared with the suicide ideation group, the FT3 level was lower in the attempted suicide group. Compared with the suicide ideation
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甄文凤,杨婧,汪晓,马向林,张庆娥.急性期老年期抑郁障碍住院患者自杀风险的相关因素分析[J].神经疾病与精神卫生,2024,24(12):837-843 DOI :10.3969/j. issn.1009-6574.2024.12.001.