伴精神行为症状阿尔茨海默病住院患者暴力攻击行为的相关因素分析
作者:
作者单位:

作者简介:

通讯作者:

基金项目:

重庆市长寿区科技计划项目 (CSKJ2024045)


Related factors of violent aggressive behavior in Alzheimer disease patients with behavioral and psychological symptoms of dementia
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的 调查伴精神行为症状(BPSD)阿尔茨海默病(AD)住院患者暴力攻击行为现状,并探 讨其相关因素。方法 回顾性分析 2023 年 3 月— 2024 年 3 月在重庆市长寿区精神卫生中心首次住院符 合 AD 诊断标准且伴 BPSD 的 126 例患者的一般资料。采用外显攻击行为量表(MOAS)、神经精神科问卷 知情者版(NPI-Q)、长谷川痴呆量表(HDS)评估患者的攻击行为、神经精神症状以及痴呆程度,根据 MOAS 加权总分将患者分为暴力行为组(MOAS 加权总分≥ 4 分,n=72)和非暴力行为组(MOAS 加权总分< 4 分,n=54),比较两组一般资料、临床资料及 NPI-Q 评分和 HDS 评分的差异,采用二元 Logistic 回归模型 分析暴力攻击行为的风险因素。结果 单因素分析结果显示,暴力行为组和非暴力行为组患者性别、病 程、吸烟史、暴力行为史、NPI-Q 评分比较,差异均有统计学意义(均P< 0.05);二分类Logistic回归分析结 果显示,性别(OR=0.281,95%CI=0.083~0.945,P=0.040)、病程(OR=0.490,95%CI=0.351~0.683,P<0.001)、 暴 力 行 为 史(OR=15.280,95%CI=3.029~77.081,P=0.001)、NPI-Q 总 分(OR=1.138,95%CI=1.034~1.253, P=0.008)是伴 BPSD 的 AD 患者暴力攻击行为的影响因素。结论 伴 BPSD 的 AD 首次住院患者暴力攻 击行为发生率较高,男性、病程短、有暴力行为史以及 NPI-Q 评分高是其危险因素。

    Abstract:

    Objective To explore the current status of violent aggressive behavior among Alzheimer's disease (AD) patients with behavioral and psychological symptoms of dementia (BPSD), and analyze its related factors. Methods The general data of 126 patients who met the diagnostic criteria for AD and BPSD during their first-time hospitalization at the Chongqing Changshou District Mental Health Hospital from March 2023 to March 2024 were retrospectively analyzed. Patients' aggressive behavior, neuropsychiatric symptoms, and degree of dementia were evaluated using the Modified Overt Aggression Scale (MOAS), Neuropsychiatric Inventory-Questionnaire (NPI-Q), and Hasegama's Dementia Scale (HDS). Patients were divided into violent aggressive group (MOAS weighted total score≥4, n=72) and non-violent aggressive behavior group (MOAS weighted total score<4,n=54) based on MOAS weighted total score, and the differences in general data, clinical data, NPI-Q score, and HDS score between the two groups were compared. Binary Logistic regression was used to analyze the risk factors of violent aggressive behavior. Results Univariate analysis showed that there were statistically significant differences in gender, disease duration, smoking history, history of violent behavior, and NPI-Q score between violent aggressive group and non-violent aggressive behavior group (all P < 0.05). Binary Logistic regression analysis showed that gender [OR=0.281, 95%CI:0.083-0.945, P=0.040], disease duration [OR=0.490, 95%CI:0.351-0.683,P < 0.001], history of violent behavior [OR=15.280, 95%CI:3.029-77.081,P=0.001], and total NPI-Q score [OR=1.138, 95%CI:1.034-1.253, P=0.008] were influencing factors of violent aggressive behavior in AD patients with BPSD, and the difference was statistically significant. Conclusions The incidence of violent aggressive behavior is high in first-time hospitalized AD patients with BPSD, and male gender, short disease duration, history of violent behavior, and high NPI-Q score are risk factors.

    参考文献
    相似文献
    引证文献
引用本文

李振阳,班晨.伴精神行为症状阿尔茨海默病住院患者暴力攻击行为的相关因素分析[J].神经疾病与精神卫生,2025,(1):62-67
DOI :10.3969/j. issn.1009-6574.2025.01.009.

复制
文章指标
  • 点击次数:
  • 下载次数:
历史
  • 收稿日期:
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2025-01-20