Objective To understand the level of negative emotions and caregiver burden of family members of schizophrenic patients in convalescence period, and to observe the effect of group psychotherapy intervention on those symptoms. Methods From the health education lectures for family members of patients with severe mental disorders organized by Harbin Mental Health Prevention and Control Office, a total of 64 family members of schizophrenic patients in convalescence period conforming to the requirements in all communities in Nangang from November 2019 to June 2020 were selected and randomly divided into trial group and control group. The trial group was given group psychological intervention once a week, for 6 weeks; the family members of the control group did not receive any interventions. The Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI), and Zarit Caregiver Burden Inventory (ZBI) were used to evaluate the intervention before and after the experiment, respectively. Results After the intervention, the BAI score (36.100±6.587) and BDI score (7.800±6.860) of family members in the trial group decreased significantly (P< 0.05) compared with those before the intervention; there was no statistically significant difference in the BAI score (46.290±13.419) and BDI score (14.280±11.231) of the family members in the control group before and after intervention (P> 0.05). After the intervention, the difference in BAI and BDI scores in the two groups was statistically significant (P < 0.05). After the intervention, the ZBI score (36.570±14.878) of family members in the trial group decreased significantly compared with that before the intervention (P < 0.05). There was no statistically significant difference in ZBI scores between the two groups (P > 0.05). Conclusions Group psychotherapy can effectively reduce the anxiety and depression levels and alleviate some of the psychological burden of family members of schizophrenic patients in convalescence period