Objective To investigate the detection of anxiety symptoms and its risk factors among medical students. Methods All undergraduate students from freshman to junior year at Hebei Medical University were selected for the study from October 19 to 28， 2021. A general profile questionnaire was used to investigate medical students' grade level， physical activity， personality characteristics， family parenting style， and academic stress， and the Generalized Anxiety Scale （GAD-7） was used to assess medical students' anxiety symptoms. Binomial Logistic regression was applied to analyze the influencing factors of anxiety symptoms in medical students and the predictive effect of the number of risk factors on anxiety symptoms in medical students. Ordered multiclass Logistic regression was applied to analyze the factors influencing the severity of anxiety symptoms in medical students and the predictive effect of the number of risk factors on the severity of anxiety symptoms in medical students. A total of 10 990 questionnaires were distributed in this study， and 9 625 valid questionnaires were collected， with an effective response rate of 87.6%. Results The detection rate of anxiety symptoms in 9 625 medical students was 29.4% （2 826/9 625）， including 83.7% （2 364/2 826） for mild anxiety symptoms， 13.4% （377/2 826） for moderate anxiety symptoms and 3.0% （85/2 826） for severe anxiety symptoms. There is a statistically significant difference in the grade， physical exercise， family rearing style， personality characteristics， and learning pressure of medical students with different anxiety symptoms （P＜0.05）. Correlation analysis shows that physical exercise， family rearing style， personality characteristics are negatively correlated with the severity of anxiety symptoms in medical students （r=-0.064， -0.120， -0.061； P ＜ 0.01）， while learning pressure is positively correlated with the severity of anxiety symptoms （r=0.277， P ＜ 0.01）. Logistic regression analysis shows that physical exercise， personality characteristics， learning pressure， family rearing style， and the number of risk factors are all influencing factors for anxiety symptoms （P＜ 0.01）. Conclusions The anxiety symptoms of medical students in school are predominantly mild，and lack of physical exercise， introversion， learning pressure and non-democratic family would increase the anxiety symptoms of medical students. The risk of anxiety symptoms increases with the number of risk factors