Patients with traumatic brain injury are confronted with further deterioration due to inflammation, edema, and ischemia leading by the primary brain injury. This downstream injury is called secondary brain injury and is often missed diagnosis in neurocritical patient, therefore, neurocritical care management is indispensable. This article reviews research progress on neurocritical care management focused on brain multimodality monitoring, cerebral perfusion pressure and cerebrovascular autoregulation, biomarkers, epilepsy prevention, mild hypothermia treatment, nutritional support, water and electrolyte imbalance.