Autoimmune encephalitis refers to a class of immune response-mediated encephalitis， and a new type of autoimmune encephalitis mediated by specific antibodies. Psychiatric disorders， as one of the main manifestations of autoimmune encephalitis， has received extensive research attention. As a subclass of mental disorders， depressive syndromes is common in clinical practice， but it has received little attention to diagnosis， treatment and prognosis. In order to enrich clinician awareness of depressive syndromes in patients with autoimmune encephalitis， this article summarizes the prevalence， pathogenesis， diagnosis， treatment and prognosis of depressive syndromes in autoimmune encephalitis.