Antibiotic related mental disorders manifest as various acute and chronic psychobehavioral abnormalities that antibiotics may induce， including visual hallucinations， delusions， mania， delirium， depression， autism spectrum disorder， attention deficit hyperactivity disorder， etc. At present， the specific effects and mechanisms of antibiotics on mental behavior have not been elucidated. This article explores the pathogenesis and research progress of antibiotic related mental disorders， aiming to deepen clinical physicians'understanding of such diseases and aid with early prevention and treatment of diseases