基于网络的认知行为疗法对少儿强迫症可行性与有效性的Meta分析
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浙江省教育科学规划课题( 2023SCG044)


Feasibility and effectiveness of internet-based cognitive behavioral therapy for children and adolescentswith obsessive-compulsive disorder: a Meta-analysis
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    目的 系统评价基于网络的认知行为疗法(ICBT)对少儿强迫症的可行性与有效性,为少 儿强迫症的临床实践提供具体可靠的循证依据。方法 计算机检索PubMed、Embase、Cochrane Library、 Web of Science、中国知网、万方数据库、维普网共7 个数据库关于ICBT对少儿强迫症疗效的研究,检索 时限为各数据库建库至2024年11月,2名研究者独立使用EndNote软件筛选符合纳入标准的研究。采用 RevMan 5.4 软件对纳入文献进行Meta 分析。结果 最终纳入10 篇文献,共纳入307 例患者,其中4 篇研 究从不同角度证明ICBT 对改善少儿的强迫症状可行性;8 篇研究阐述ICBT 对少儿强迫症有效性。结果 显示:干预后强迫症状评分的组间比较,与对照组比较,ICBT干预可显著降低少儿强迫症状评分(MD= -5.81,95%CI:-11.11~-0.51,P < 0.05);长期随访后强迫症状评分的组间比较,以暴露与反应预防 (ERP)为主要内容的ICBT治疗,在长期随访前后强迫症状评分差异有统计学意义(MD=2.71,95%CI: 0.88~4.54,P< 0.05);非以ERP为主要内容进行ICBT治疗,在长期随访前后强迫症状评分差异无统计 学意义(MD=1.39,95%CI:0.12~2.65,P> 0.05)。结论 ICBT 对改善少儿的强迫症状具有可行性、可接 受性,疗效显著、疗效维持时间较长,具有较好的临床应用前景。

    Abstract:

    Objective To systematically evaluate the feasibility and effectiveness of internet-based cognitive behavioral therapy( ICBT) for children and adolescents with obsessive-compulsive disorder( OCD), so as to provide a specific and reliable evidence-based basis for clinical practice in children and adolescents with OCD. Methods The study on the efficacy of ICBT in children and adolescents with OCD was electronically searched in 7 databases, including PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, WanFang Data, and VIP. The search period was from database establishment to November 2024. Two investigators independently used EndNote to screen studies that met the inclusion criteria. Meta-analysis of the included literature was performed using RevMan 5.4. Results A total of 10 papers were included with a total of 307 patients. Four studies demonstrated the feasibility of ICBT for improving obsessivecompulsive symptoms in children and adolescents from different perspectives. Eight studies demonstrated the effectiveness of ICBT for children and adolescents with OCD. The results showed that compared with control group, ICBT significantly reduced post-intervention obsessive-compulsive symptom scores of children and adolescents, and the difference was statistically significant[ MD=-5.81, 95%CI( -11.11,-0.51), P<0.05]. When comparing between groups after long-term follow-up, the difference in obsessive-compulsive symptom scores before and after long-term follow-up was statistically significant for ICBT with exposure and response prevention( ERP) as the main component[ MD=2.71, 95%CI( 0.88, 4.54), P < 0.05]. The difference in obsessive-compulsive symptom scores before and after long-term follow-up was not statistically significant for ICBT with non-ERP as the main component[ MD=1.39, 95%CI( 0.12, 2.65), P>0.05]. Conclusions ICBT is feasible and acceptable for improving obsessive-compulsive symptoms in children and adolescents, with significant efficacy and long duration of efficacy maintenance, and has good prospects for clinical application.

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韩佳琪,张婷,朱春乐,解凯旋.基于网络的认知行为疗法对少儿强迫症可行性与有效性的Meta分析[J].神经疾病与精神卫生,2025,25(8):561-568
DOI :10.3969/j. issn.1009-6574.2025.08.005.

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  • 在线发布日期: 2025-08-20