天津市“免费服药政策”对社区贫困严重精神障碍患者服药依从性影响
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天津医科大学2023年度医院管理创新项目( 2023YG28)


Impact of "Free Medication Policy" on medication adherence of impoverished patients with severemental disorders in the Tianjin community
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    目的 评估天津市“免费服药政策”实施对社区贫困严重精神障碍患者服药依从性的影 响。方法 选取2021 年“天津市精神卫生信息系统”中14 935 例贫困严重精神障碍患者为研究对象。 比较参加“免费服药政策”的3 722 例贫困严重精神障碍患者与未参加“免费服药政策”的11 213 例贫困 严重精神障碍患者在服药依从性方面的差异,并分析影响服药依从性的相关因素。采用多因素Logistic 回归分析是否参加“免费服药政策”对患者服药依从性的影响。结果 14 935 例贫困严重精神障碍患 者中参加“免费服药政策”的有3722 例(24.92%)。参加“免费服药政策”患者的规律服药比例95.43% (3 552/3 722)明显高于未参加患者的87.75%(9 839/11 213),差异有统计学意义(χ2=178.09,P < 0.01)。 参加“免费服药政策”的患者规律服药的概率是未参加政策患者的2.72倍(OR=2.72,95%CI:2.29~3.23)。 既往有危险行为(OR=1.36,95%CI:1.01~1.84)、曾住院(OR=1.16,95%CI:1.02~1.32)是患者规律服药 的保护性因素;患精神分裂症(OR=0.80,95%CI:0.69~0.92)、弱监护(OR=0.73,95%CI:0.61~0.87)是患 者规律服药的危险因素。结论 “免费服药政策”提高了社区贫困严重精神障碍患者的服药依从性,在 社区防治工作中要重点关注精神分裂症患者、弱监护患者的服药情况,要加大政策宣传和引导。

    Abstract:

    Objective To evaluate the impact of "Free Medication Policy" in Tianjin on medication adherence among impoverished patients with severe mental disorders in the community. Methods A total of 14 935 impoverished patients with severe mental disorders in the 2021 Tianjin Mental Health Information System were selected as research subjects. The differences in medication adherence between 3 722 impoverished patients with severe mental disorders who participated in the "Free Medication Policy" and 11 213 impoverished patients with severe mental disorders who did not participate in the "Free Medication Policy" were compared, and the relevant factors of medication adherence were analyzed. Logistic multiple regression was used to analyze the impact of "Free Medication Policy" on patients' medication adherence. Results Among 14 935 impoverished patients with severe mental disorders, 3 722( 24.92%) participated in the "Free Medication Policy". The proportion of patients who participated in the "Free Medication Policy" taking medication regularly was 95.43%(3 552/3 722), which was significantly higher than the 87.75%( 9 839/11 213) of patients who did not participate, and the difference was statistically significant( χ2=178.09, P< 0.01). The probability of patients participating in the "Free Medication Policy" taking medication regularly was 2.72 times that of patients who did not participate in the policy[ OR=2.72, 95%CI( 2.29,3.23)]. Previous risky behavior[ OR=1.36, 95%CI( 1.01, 1.84)] and hospitalization[ OR=1.16, 95%CI( 1.02,1.32)] were protective factors for patients taking medication regularly, and schizophrenia[ OR=0.80, 95%CI( 0.69,0.92)] and weak monitoring[ OR=0.73, 95%CI( 0.61, 0.87)] were risk factors for patients taking medication regularly. Conclusions The "Free Medication Policy" improves the medication adherence of impoverished patients with severe mental disorders in the community. In community prevention and control work, special attention should be paid to the medication situation of patients with schizophrenia and weak monitoring, and policy promotion and guidance should be increased.

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张宝霞,张佩佩.天津市“免费服药政策”对社区贫困严重精神障碍患者服药依从性影响[J].神经疾病与精神卫生,2025,25(9):652-658
DOI :10.3969/j. issn.1009-6574.2025.09.007.

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  • 在线发布日期: 2025-09-16