青少年抑郁障碍患病现状及治疗模式研究进展
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北京市西城区社科联课题研究( XCSKL-2025011)


Research progress on the prevalence and therapy modes of depressive disorders in adolescents
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    摘要:

    目前,青少年抑郁障碍已成为全球范围内重要的公共卫生问题,其患病率呈持续上升趋 势,自伤、自杀等风险较高,严重影响青少年的身心发展和社会功能。青少年抑郁障碍的发生与个体心 理特征、神经发育与生物学异常、家庭环境及社会因素等多方面密切相关,其发病机制涉及神经生理调 控、心理认知易感及环境应激等复杂交互。心理治疗、药物治疗及家庭-学校-医院协同干预已成为其 主要治疗模式,但临床实践中仍存在早期识别不足、个体化治疗水平有限及长期康复支持体系不完善 等问题。现从青少年抑郁障碍的患病现状、影响因素、发病机制、治疗模式及临床应用问题等方面进行 综述,旨在为青少年抑郁障碍的早期防控、规范化诊疗及综合干预体系建设提供参考。

    Abstract:

    Currently, depressive disorders among adolescents have become a major public health issue worldwide, with a continuously increasing prevalence and a high risk of self-injury and suicide, severely affecting adolescents' physical and mental development as well as their social functioning. The onset of depressive disorders in adolescents is closely linked to a variety of factors, including individual psychological characteristics, neurodevelopmental and biological abnormalities, family environment, and social factors. Its pathogenesis involves complex interactions among neurophysiological regulation, psychological and cognitive vulnerability, and environmental stressors. Psychotherapy, drug therapy, and collaborative interventions involving families, schools, and hospitals have become the primary treatment modes; however, clinical practice still faces challenges such as insufficient early identification, limited individualized treatment, and an inadequate long-term rehabilitation support system. This paper reviews the epidemiological characteristics, influencing factors, pathogenesis, treatment modes and clinical application issues of depressive disorders in adolescents, with the aim of providing guidance for the early prevention and control, standardized diagnosis and treatment, and the development of a comprehensive intervention system for depressive disorders in adolescents

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许璐,闫芳. 青少年抑郁障碍患病现状及治疗模式研究进展[J]. 神经疾病与精神卫生,2026,26(9):651-657. DOI:10.3969/j. issn.1009-6574.2026.09.006.

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  • 在线发布日期: 2026-09-22