Effects of transcranial magnetic stimulation on the memory function and the ability of mental behavior of Alzheimer disease patients
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    Abstract:

    Objective To investigate the effects of transcranial magnetic stimulation on the treatment of patients with memory impairment AD and the effects on the ability of mental behavior. Methods A total of 60 cases of AD patients with memory impairment who were treated in Nanchong Physical and Mental Hospital from December 2016 to June 2017 were recruited and randomly divided into control group and rTMS group. The control group was given conventional drug therapy, and the rTMS group was treated with transcranial magnetic stimulation on the basis of conventional drug therapy. The therapeutic effects of the two groups were observed and compared, including the incidence of 12 symptoms of the ability of mental behavior before and after treatment, ability of daily living and Montreal Cognitive Assessment( MoCA). Results The effective rate of rTMS group was 93.33%, which was significantly higher than that of the control group( 70.00%)( χ2=5.455, P=0.020). There was no significant difference in the 12 symptoms of the ability of mental behavior between the two groups before treatment. After treatment, the incidence of vehemence, depression, anxiety, euphoria, indifference, depressor, irritability, sleep nocturnal behavior, hyperactivity of appetite and eating disorder was significantly lower than that of the control group, and the differences were statistically significant( P< 0.05). The score of ability of daily living of the rTMS group was higher than that of the control group after treatment, and the difference was statistically significant( P< 0.01). The vital signs of the two groups were stable in the course of treatment, and no headache, tinnitus or other adverse events occurred. Conclusions Transcranial magnetic stimulation has a food therapeutic effect on AD patients with memory impairment, and can significantly improve the patients' ability of mental behavior and daily life, which is of great clinical application value.

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Yi CY,Chen SY,Zhang H,et al. Effects of transcranial magnetic stimulation on the memory function and the ability of mental behavior of Alzheimer disease patients[J].Journal of Neuroscience and Mental Health,2018,18(10):710-713.DOI:10.3969/j. issn.1009-6574.2018.10.006.

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  • Online: April 19,2018
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