Objective To investigate the effects of computerized cognitive remediation therapy （CCRT） on cognition function， symptoms and conversion in ultra-high-risk（ UHR） patients of schizophrenia. Methods A total of 112 UHR individuals and first-degree relatives of schizophrenia were selected from the outpatient department of the Seventh People's Hospital of Dalian from March 2016 to February 2017. According to the random number table， the research subjects were divided into CCRT group（ 57 cases） and control group （55 cases）. The subjects in the two groups were given CCRT intervention and health education respectively from 3 months. The cognitive function assessment and symptom assessment were carried out at baseline， the 3rd， and the 12th month after intervention using MATRICS Consensus Cognitive Battery（ MCCB） and the Scale of Prodromal Symptoms（ SOPS）. The conversion assessments was conducted at the 3rd，6th and 12th months， and the conversion rates were compared. Results After intervention， the four dimensions of information processing speed， attention/alertness， working memory and reasoning and problem-solving ability in the MCCB score of the CCRT group were significantly improved. There were statistical differences between the two groups after intervention， and the differences before and after intervention were statistically significant（ P ＜ 0.05）. The positive symptoms and disintegration symptoms of SOPS in the CCRT group were significantly improved compared with baseline and control group， and lasted for 12 months（ P ＜ 0.05）. The conversion rate of both groups showed an upward trend. At the 3rd and 6th month， the control group（ 12.7%， 18.1%） was significantly higher than the CCRT group（ 5.3%， 1.8%）， and the difference was statistically significant（ P＜ 0.05）. At the 12th month， the control group（ 20.0%） was still higher than the CCRT group（ 12.3%）， but the difference was not statistically significant（ P＞ 0.05）. Conclusions CCRT intervention in UHR patients with schizophrenia can effectively improve their cognitive function， positive symptoms and reduce conversion rate to some extent. The long-term efficacy needs further verification.