Objective To analyze the related factors of high suicide risk in female inpatients with bipolar disorder （BD）. Methods The medical records of 378 female BD inpatients in Beijing Anding Hospital Affiliated to Capital Medical University from April 2010 to June 2019 were collected. Patients were divided into low suicide risk group （n=220） and high suicide risk group （n=158） according to their suicide risk. The differences of general demographic data and clinical characteristics between the two groups were compared. Binomial Logistic regression analysis was used to explore the related factors of high suicide risk in female BD inpatients. Results Compared with the low suicide risk group， the patients in the high suicide risk group had significantly reduced length of hospital stay，younger age of first onset and younger age of first depressive episode，increased total number of episodes and number of depressive episodes，decreased number of manic episodes， increased proportion of patients with onset symptoms of depression and bipolar Ⅱ disorder （BD-Ⅱ）， and lower proportion of patients with psychotic symptoms， and the differences were statistically significant （all P ＜ 0.05）. Binomial Logistic regression analysis showed that the number of depressive episodes （OR=1.56， 95%CI=1.32-1.83）， types of BD （OR=2.30， 95%CI=1.16-4.58） and with or without psychotic symptoms （OR=0.56， 95%CI=0.35-0.90） were related to the high suicide risk in female patients with BD （P ＜ 0.05）. Conclusions The frequent depressive episodes， BD- Ⅱ and without psychotic symptoms were the factors influencing the high risk of suicide in female patients with BD.