Panic disorder is an acute anxiety disorder characterized by recurrent panic attacks， which seriously affects the social functioning and quality of life of patients. Currently， the pathogenesis of panic disorder is not clear. Studies show that anxiety sensitivity is a susceptibility factor for panic attacks， and high levels of anxiety sensitivity are positively correlated with the severity of panic disorder， leading to poor prognosis for patients. This paper reviews the characteristics of anxiety sensitivity in patients with panic disorder and the role of anxiety sensitivity in the occurrence， progression， and intervention of panic disorder， so as to provide a perspective for clinical diagnosis and treatment of panic disorder.