Childhood trauma has a certain correlation with resting blood pressure and resting heart rate， which is an important risk factor for predicting cardiovascular disease. This review summarizes the correlation between childhood trauma and resting blood pressure and resting heart rate and cardiovascular disease， as well as the potential mechanisms of childhood trauma affecting resting blood pressure， resting heart rate and cardiovascular disease， including epigenetics， neuroendocrine， oxidative stress， inflammation， adverse lifestyle， psychological stress etc. The aim is to clarify the potential impact of childhood trauma on the cardiovascular system， and provide a theoretical basis for the prevention and treatment of cardiovascular disease