The incidence of depressive disorder in adolescents is increasing year by year， which not only affects their mental health development， but also brings serious burdens to families and society. At present， the etiology of depressive disorder is not yet clear， and its diagnosis mainly relies on symptomatology， lacking objective basis. Magnetic resonance imaging （MRI） and other brain imaging techniques are widely used to explore neurobiological markers related to depressive disorder， which are of great significance for early detection， diagnosis， treatment， prognosis， and treatment response prediction of diseases. This paper reviews the research on brain structural imaging of adolescents with depressive disorders in recent years.