Schizophrenia is a common severe mental disorder， and varying degrees of cognitive impairment are present in the majority of people with schizophrenia. However， the physiological and behavioral functions underlying cognitive impairment and the mechanisms for improving and enhancing cognitive performance are unknown. Recent studies have indicated that abnormalities in sleep spindles may be closely related to cognitive impairment. Deficient spindles may lead to cognitive impairment in patients with schizophrenia by altering memory consolidation， reasoning， and executive abilities. Elucidating the correlation between spindles and cognitive function may provide new ideas for the clinical diagnosis and treatment of cognitive impairment in schizophrenia.